IBM Heron r2 · ibm_fez · 46 qubits · Mastoparan I (IDWKKLLDAAKQIL)

A single-pass polycontextural folding circuit
fully audited

Miyazawa–Jernigan folding physics compiled into one polycontextural circuit and run once per mode on IBM Fez (46 logical qubits). Compilation, portability, and a full tier audit, published with eight IBM job IDs and a matching random-repair control.

+13.5
QPC raw best (Tier A)
Heron r2 heavy-hex
−4.19
IonQ raw mean (Tier A)
their per-shot signal
−9.74
QPC after repair (Tier D)
−10.65
Random control, same repair
published with the audit

The control is on the page. Uniform random bitstrings through the same Tier D repair reach −10.65. QPC Fez repair is −9.74. Literature Eref is −8.698. All three sit with the eight public IBM job IDs.

Plain English

What this test is
Fold mastoparan I (46 logical qubits) in one polycontextural pass on IBM Fez. Miyazawa–Jernigan physics compiled once, one schedule per mode.
Why we did it
Cross-vendor portability and audit: the same QPC layer exports to IBM, IonQ, Pasqal, IQM, Azure, Origin. This page is the Fez audit trail.
What QPC computed
Tiers A–D separately · 8 public IBM job IDs · random bitstring control through the same repair pipeline (−10.65).
Headline result
Single-pass compilation on Heron r2. QPC repair energy −9.74. Random repair −10.65 published beside it. Architecture: one circuit, one readout family.
What this page delivers
Single-pass polycontextural compilation, portable export, and a full public audit on ibm_fez.

What this run shows

Supported by the data

  • Single-pass compilation. Geometry-contact coupling in one fixed schedule via transjunctions. Eight IBM job IDs are public.
  • Portability. The same polycontextural layer exports to IBM, IonQ, IQM, Pasqal, and Origin.
  • Full auditability. Tiers A–D separately, plus random-repair control (IonQ Fig. 4 analogue), with public job IDs.

Numbers on the record

  • QPC Tier A best: +13.5 on Fez heavy-hex.
  • QPC Tier D repair: −9.74.
  • Random repair (same code): −10.65 (best seed).
  • IonQ literature: raw mean ≈ −4.19 · consensus ≈ −8.698 · Eref −8.698.

What the IonQ team did

Kipu Quantum and IonQ reported BF-DCQO for protein-inspired models on trapped-ion hardware (46–61 qubits), using multi-body HUBO encodings and a hybrid loop: repeated quantum executions plus classical consensus / repair over samples (their Fig. 4 addresses when repair alone carries the signal). arXiv:2604.26861

IonQ stack (quantum + classical)

What QPC does in one pass

QPC compiles the same Miyazawa–Jernigan physics into a fixed polycontextural circuit and submits it once per mode to IBM Runtime. Geometry and contact structure sit in one schedule.

Circuit construction, transjunction wiring, and gate schedules are proprietary. Public evidence on this page: tier energies, random-repair controls, and verifiable IBM job IDs.

Results with audit controls (40 960 Fez shots)

Tier / metric IonQ BF-DCQO (literature) QPC Fez (8 jobs merged) Random control
Tier A · best raw sample Mean ≈ −4.19 (per-shot ions) +13.5 (Heron r2 heavy-hex) +8.77 best (seed 7); +8.8 to +15.8 range
Pool quality · mean of best 200 unique outcomes before repair Literature reports consensus at Tier D Elite pool mean vs uniform random (~31) ~31 (uniform random; seeds 42, 7, 2026)
Tier D · same repair on sample pool Consensus ≈ −8.698 −9.74 −7.96 / −10.65 / −9.74 (seeds 42, 7, 2026)
Eref (reference fold) −8.698
Verifiability Published 8 job IDs Random Tier D control on the results page
Audit (IonQ Fig. 4 analogue): The same Tier D repair applied to 40 960 uniform random bitstrings (no IBM jobs). Best random seed reaches −10.65. This page delivers single-pass polycontextural encoding, portable circuits, and open controls, with every number in the table.

Summary: IonQ’s literature lead on this instance is the raw per-shot ion signal under iterative BF-DCQO. QPC’s contribution is a compact, portable, single-pass encoding on IBM Heron r2, with every tier and the random control published at equal weight.

Six-sequence panel (paper Table I): The IonQ/Kipu study benchmarks six peptides (46–61 qubits). This release is the full audited Fez campaign on IDWKKLLDAAKQIL.

Eref and Tier D: IonQ’s arXiv:2604.26861 gives Eref = −8.698 from a converged classical genetic algorithm on the Robert et al. tetrahedral MJ Hamiltonian. QPC Tier D (−9.74) applies the same repair code to Fez bitstrings. The random audit (best Tier D −10.65) sits in the same table so the repair channel is readable on its own.

Why QPC for complex optimization

QPC on IonQ hardware

This page reports energies on IBM Fez. QPC already runs verifiable workloads on IonQ Forte (Azure Quantum, Braket). Joint benchmarks of the same 46Q polycontextural protein circuit on IonQ are welcome.

Invitation to the IonQ / Kipu line of work

The trapped-ion BF-DCQO result is a major achievement. QPC asks a complementary architecture question: can the same folding physics be encoded as a fixed polycontextural circuit on any QPU, with open job IDs and a published random-repair control? We publish that control so reviewers can ask the same questions IonQ answered in Fig. 4. Joint benchmarks on IonQ using exported QPC circuits are welcome.

Artifacts & full data

Sequence IDWKKLLDAAKQIL · Backend ibm_fez · IBM Heron r2

→ Full results tables, all 8 job IDs, audit seeds